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Yet the consequences are unknown Bioavailability: there are four specific metabolic steps necessary to convert cyanocobalamin into one of the coenzyme forms, which is a clear metabolic disadvantage (3) Utilisation problems: certain hereditary diseases, as well as metabolic disorders, prevent the conversion of cyanocoalamin into the active B12 forms (4) Steals methyl groups: cyanocobalamin requires a methyl group to convert into methylcobalamin, which it takes from the important amino acid S-adenosylmethionine (SAM)
10.1111/j.1471-4159.2007.04837.x 33 FarooqueU.OkorieN.KatariaS.ShahS
Data availability The datasets generated during and/or analyzed during the current study are available from the corresponding author (e-mail: [email protected]) on reasonable request
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